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Document Type

Original Study

Abstract

The present study has been designed to Determining the prevalence and risk factors of Toxoplasma gondii in patients with rheumatoid arthritis. All samples of the experiment were taken from cephalic vein in non-heparinized tubes, at the conclusion of each treated and control period, all samples collection from Al-Dewaniyah Hospital, and from clinical private from July-2022 to Feb. 2023. The experiment was designed and divided into two groups, a group of healthy people and a group of people infected with rheumatoid arthritis with infection with Toxoplasma gondii. 1. Healthy group: 100 samples from peoples without any disease or treatment. 2. Patients group: 100 samples from peoples' patients treated and untreated with rheumatoid arthritis with infection of Toxoplasma gondii. The current study showed that 33 (33%) of patients were seropositive for Toxoplasma IgG, while all controls with seronegative for Toxoplasma IgG. Seropositivity of Toxoplasma Abs IgG showed significant differences between patients and control groups p value (0.0254). The current study showed that 33 (33%) of patients were seropositive for Toxoplasma IgG, while all controls with seronegative for Toxoplasma IgG. Seropositivity of Toxoplasma Abs IgG showed significant differences between patients and control groups p value (0.0254). Distribution of Toxoplasma IgG antibodies according to age groups showed that the higher ratio of Toxoplasma antibodies was found in age group > 51 years. In addition, there was no significant between the Toxoplasma IgG seropositive and age groups of patient's arthritis. The present results showed no significant association between seropositivity of Toxoplasma antibodies and area of residence, in urban areas, there were 48 patients with arthritis and 12 with toxoplasmosis, while in rural areas, 52 patients with arthritis and 21 had toxoplasmosis.

Keywords

IgG, Rheumatoid factor, Anti-CCP, ESR, T. gondii

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