Document Type
Article
Abstract
Oxidative stress occurs as a result of disturbance in the balance between the production of reactive oxygen species (free radicals) and antioxidant defenses. Markers of oxidative stress were measured the markers of oxidative stress in breast cancer patients after diagnosis of breast cancer and compared these plasma blood levels controls This study was conducted to three markers of oxidative stress ;these are (SOD) enzyme ,malondialdehyde (MDA)and8-iso-prostaglandinF2α plasma of patients with breast cancer and compare with controls .In this study ; the mean MDA (ng/ml) levels for the breast cancer patients and the controls were55.91±3.31 and40.61±3.76 respectively, while the SOD (pg/ml) levels were1530.37±80.4 and1851.4 9±93.65 respectively and the 8-iso-PGF2α (ng/ml ) levels were 40.16±3.31 and 30.16±2.34 difference of the mean were statistically significant (p value <0.05).
Keywords
Breast cancer, Malondialdehyde, 8-iso-PGF2α, Oxidative stress, Superoxide dismutase
Recommended Citation
Jabir, Ferdous Abbas and Shaker, Ahmed Sabah
(2020)
"Roles of Superoxide dismutase (SOD),Malondialdehyde (MDA),8-iso-prostaglandin F2α ( 8-iso-PGF2α) as oxidative stress in development and progression of Brest cancer in Iraqi females patients,"
Al-Qadisiyah Journal of Pure Science: Vol. 25
:
No.
1
, Article 13.
Available at:
https://doi.org/10.29350/2411-3514.1218