The Co-infection of pulmonary Mycosis with Tuberculosis among Iraqi patients: A cross-sectional study

Mahmood Yaseen Mukhlif, Department of Microbiology, College of Medicine, University of Anbar, Anbar, IraqFollow
Yassir M. Abdulateef, Department of Microbiology, College of Medicine, University of Anbar, Anbar, Iraq
Sawsan Qahtan Taha Al-Quhli, Department of Microbiology, College of Medicine, University of Anbar, Anbar, Iraq

Document Type

Original Study

Abstract

Background and aim of study: Pulmonary tuberculosis is a serious airborne-transmitted infectious disease that is caused by significant threat pathogenic bacteria known as Mycobacterium tuberculosis and is amongst the top ten of the deadliest single infectious agents globally. Pulmonary mycosis is a lung fungal infection that is common among patients who suffer from immune system suppression. PTB and PM have exhibited similar or coordinated risk factors. Furthermore, recent studies have assumed PTB as a significant PM risk factors. Pulmonary tuberculosis patients were frequently suggested to have pulmonary fungal coinfection that increased the rate of mortality. This study aimed to assess the pulmonary mycosis co-infection prevalence in pulmonary tuberculosis Iraqi patients. Materials and Methods: A cross-sectional study carried out from February to July 2023. The study included 150 participants from patients suspected of having pulmonary tuberculosis. Two early morning sputum samples were obtained from each participants. Tuberculosis has been identified using GeneXpert system, whereas mycotic infections have been detected using conventional methods including KOH, culture, and Lactophenol blue stain. Results: Among 150 Iraqi participants 66.7% (100/150) were positive for PTB, 60 % (90/150) were positive for fungal pathogen. Pulmonary tuberculosis fungal co-infection among PTB patients was seen in 81% (81/100). Candida was the predominant species participating in pulmonary mycosis. There was a statistically significant association between pulmonary mycosis and PTB (p

Keywords

Tuberculosis, Mycobacterium tuberculosis, Pulmonary mycosis, fungal coinfections, candida, Aspergillus

Recommended Citation

Mukhlif, Mahmood Yaseen; Abdulateef, Yassir M.; and Taha Al-Quhli, Sawsan Qahtan (2024) "The Co-infection of pulmonary Mycosis with Tuberculosis among Iraqi patients: A cross-sectional study," Al-Qadisiyah Journal of Pure Science: Vol. 30 : No. 1 , Article 13.
Available at: https://doi.org/10.29350/2411-3514.1274